ZENIFER CAPSULE
November 10, 2017ZART DP TABLET
November 10, 2017
| ZART FORTE TABLET |
Artemether 80 mg & Lumefantrine 480 Tablets |
| Composition : |
Each un-coated tablet contains Artemether 80 mg & Lumefantrine 480 mg. |
| Indications : |
For treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5 kg bodyweight and above.
Zart Forte Tablets have been shown to be effective in geographical regions where resistance to chloroquine has been reported
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| Contraindications : |
It is contraindicated in:
• Patients with known hypersensitivity to the active substances or to any of the excipients.
• Patients with severe malaria according to WHO definition.
• Metoprolol, imipramine, amitryptyline, clomipramine.
• Patients with a family history of sudden death or of congenital prolongation of the QTc interval on electrocardiograms, or with any other clinical condition known to prolong the QTc interval.
• Antiarrhythmics of classes IA and III,
- Neuroleptics, antidepressive agents,
- Macrolides, fluoroquinolones, imidazole and triazole antifungal agents,
- terfenadine, astemizole,cisapride, flecainide.
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| Adverse Effects : |
Hypersensitivity, Decreased appetite, Sleep disorders, Insomnia, Headache, Dizziness, Paraesthesia, Ataxia, hypoesthesia, Somnolence, Palpitations, Vomiting, Abdominal pain, Nausea, Diarrhoea |
| Dosage : |
Dosage in Adult Patients (>16 years of age)
A 3-day treatment schedule with a total of 6 doses is recommended for adult patients with a bodyweight of 35 kg and above
Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice-daily (morning and evening) for the following 2 days (total course of 24 tablets).
Dosage in Pediatric Patients
5 kg to less than 15 kg bodyweight:
One tablet as an initial dose, 1 tablet again after 8 hours and then 1 tablet twice-daily (morning and evening) for the following 2 days (total course of 6 tablet
15 kg to less than 25 kg bodyweight:
Two tablets as an initial dose, 2 tablets again after 8 hours and then 2 tablets twice-daily (morning and evening) for the following 2 days (total course of 12 tablets).
25 kg to less than 35 kg bodyweight:
Three tablets as an initial dose, 3 tablets again after 8 hours and then 3 tablets twice-daily (morning and evening) for the following 2 days (total course of 18 tablets).
35 kg bodyweight and above:
Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice-daily (morning and evening) for the following 2 days (total course of 24 tablets).
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