CEFTIMED INJECTION 250 mg/1g
November 9, 2017CEFOTAZ INJECTION 250 mg/500mg/1 gm
November 9, 2017
| CEFOTEM INJECTION 250 mg/500mg/1 gm |
Cefotaxime Injections |
| Composition : |
Each vial of Cefotem 250 contains Cefotaxime sodium (Sterile)
equivalent to Cefotaxime 250 mg.
Each vial of Cefotem 500 contains Cefotaxime sodium (Sterile)
equivalent to Cefotaxime 500 mg.
Each vial of Cefotem 1 gm contains Cefotaxime sodium (Sterile) equivalent to Cefotaxime 1 gm. |
| Indications : |
It is indicated in the treatment of serious infections, either before the infecting organism has been identified or when caused by bacteria of established sensitivity, including osteomyelitis, septicemia, bacterial endocarditis, meningitis, peritonitis. and other serious bacterial infections suitable for parenteral antibiotic therapy.
It may be used for pre-operative prophylaxis in patients undergoing surgical procedures, that may be classified as contaminated or potentially so. |
| Contraindications : |
In patients with allergy to Cephalosporin. In patients hypersensitive to penicillin, the possibility of allergic cross reactions should be borne in mind. |
| Adverse Effects : |
Diarrhoea, nausea, vomiting; neutropenia, eosinophilia, anaemia, rash, pruritus, fever, chills, local reactions (e.g. pain, induration, ecchymosis, tenderness at inj site). Rarely, pancreatitis, hypoprothrombinaemia. |
| Dosage : |
Adults:
The recommended dosage for mild to moderate infections is 1g 12 hourly. However, dosage may be varied according to the severity of the infection, sensitivity of causative organisms and condition of the patient. Therapy may be initiated before the results of sensitivity tests are known.
In severe infections dosage may be increased up to 12g daily given in three or four divided doses. For infections caused by sensitive Pseudomonas species daily doses of greater than 6g will usually be required.
Children:
The usual dosage range is 100-150mg/kg/day in two to four divided doses. However, in very severe infection doses of up to 200mg/kg/day may be required.
Neonates: The recommended dosage is 50mg/kg/day in two to four divided doses. In severe infections 150-200mg/kg/day, in divided doses, have been given.
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